RSV and Synagis

What is RSV?

Respiratory syncytial virus (RSV) is a virus that causes a lung infection called bronchiolitis. Babies commonly get RSV. Two out of three infants are infected with RSV during their first year of life. RSV is highly contagious. It is spread by contact with infected fluids from the nose or mouth and through droplets in the air from coughing. RSV usually occurs in the wintertime.

Some children with RSV may have pneumonia or they need oxygen. Children born prematurely or who get RSV during the first months of life are more likely to have these complications.

Toddlers and older children with RSV usually do not have serious problems. For these children, RSV is usually no worse than a bad cold.

A vaccine is not available for RSV, but a medicine called Synagis can help prevent lung infections.

What is Synagis?

Synagis is a medicine that helps prevent serious lung infections caused by RSV. Synagis is an antibody that is made using DNA technology.

This medicine is not a treatment for children who already have RSV.

Should my child get Synagis?

This medicine is given only to children under 2 years old at high risk for serious complications when they get RSV. These children include:

  • some premature infants who were born at least 5 weeks early
  • children with bronchopulmonary dysplasia (BPD)
  • children with other conditions that put them in a high-risk group.

Synagis should not be given to children who have had a severe allergic reaction to Synagis before.

Check with your health care provider if you have questions about whether your child should receive Synagis.

How is Synagis given?

Synagis is given with a shot into the leg muscle. Your child must get a shot every month throughout the winter and early spring. Synagis may be given with other routine immunizations.

What are the side effects of Synagis?

The place where the shot was given may become red or tender. Your child has a slight risk of vomiting or having diarrhea. Rarely, children develop cold symptoms, an ear infection, rash, pain, or sore throat. As with any medicine, there is a risk that it could cause an allergic reaction.

How can I learn more?

Ask your health care provider about Synagis. He or she can give you the package insert or suggest other sources of information.


Written by Robert Brayden, MD, Associate Professor of Pediatrics, University of Colorado School of Medicine.
Published originally by McKesson Health Solutions LLC.
Adapted by Premier Care Pediatrics, PA.
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.